arrow
arrow
arrow
The major products A and B in the following reaction sequence are
Question

The major products A and B in the following reaction sequence are

A.

B.

C.

D.

Correct option is A

The addition-elimination mechanism

​The mechanism involves addition of the nucleophile followed by elimination of the leaving group—the addition–elimination mechanism. It is not necessary to have a carbonyl group—any electron-withdrawing group will do—the only requirement is that the electrons must be able to get out of the ring into this anion-stabilizing group. Here is an example with a para-nitro group.

​Everything is different about this example—the nucleophile (HO-), the leaving group (Cl-), the anion-stabilizing group (NO2), and its position (para)—but the reaction still works. The nucleophile is a good one, the negative charge can be pushed through on to the oxygen atom(s) of the nitro group, and chloride is a better leaving group than OH.

A typical nucleophilic aromatic substitution has:

a. an oxygen, nitrogen, or cyanide nucleophile

b. a halide for a leaving group

c. a carbonyl, nitro, or cyanide group ortho or para to the leaving group

Here is an example with RO- attacking a nitrated aniline.

test-prime-package

Access ‘CSIR NET Chemical Sciences’ Mock Tests with

  • 60000+ Mocks and Previous Year Papers
  • Unlimited Re-Attempts
  • Personalised Report Card
  • 500% Refund on Final Selection
  • Largest Community
students-icon
353k+ students have already unlocked exclusive benefits with Test Prime!
test-prime-package

Access ‘CSIR NET Chemical Sciences’ Mock Tests with

  • 60000+ Mocks and Previous Year Papers
  • Unlimited Re-Attempts
  • Personalised Report Card
  • 500% Refund on Final Selection
  • Largest Community
students-icon
353k+ students have already unlocked exclusive benefits with Test Prime!
Our Plans
Monthsup-arrow