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    For a person weighing 70kg the minimal volume (in mL) of a fatal dose of a compound with LD50=80mgkg-1, and density=1.45gmL-1is ​
    Question

    For a person weighing 70kg the minimal volume (in mL) of a fatal dose of a compound with LD50=80mgkg-1, and density=1.45gmL-1is

     


    A.

    5.6

    B.

    3.9

    C.

    0.8

    D.

    0.4

    Correct option is B

    ​In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation. Because resistance varies from one individual to another, the "lethal dose" represents a dose (usually recorded as dose per kilogram of subject body weight) at which a given percentage of subjects will die. The lethal concentration is a lethal dose measurement used for gases or particulates. The LD may be based on the standard person concept, a theoretical individual that has perfectly "normal" characteristics, and thus not apply to all sub-populations.

    The median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity. A lower LD50 is indicative of increased toxicity.


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