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    The sequence through which the following reaction proceeds is
    Question

    The sequence through which the following reaction proceeds is

    A.

    Claisen rearrangement, tautomerization, and Cope rearrangement

    B.

    Claisen rearrangement, aza-Claisen rearrangement, and tautomerization

    C.

    Cope rearrangement, Claisen rearrangement, and tautomerization

    D.

    Claisen rearrangement, tautomerization, and aza-Claisen rearrangement

    Correct option is A

    ​The Claisen rearrangement is a powerful carbon–carbon bond-forming chemical reaction. The heating of an allyl vinyl ether will initiate a [3,3]-sigmatropic rearrangement to give a γ,δ-unsaturated carbonyl.

    ​The above Claisen rearrangement is two step reaction. The first step in this reaction is [3, 3] sigmatropic rearrangement. 

    ​This is one step mechanism without ionic intermediates. In this case numbering start from the heteroatom oxygen having σ (sigma) bond and allylic carbon of the allyl group. The second step in the reaction is a simple ionic proton transfer to regenerate aromaticity.

    Cope rearrangement

    The thermal rearrangement of 1, 5-dienes by [3, 3] sigmatropy is called Cope rearrangement. The reaction proceeds in the thermodynamically favoured direction.


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