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    Monozygotic and dizygotic twins are used to study the onset of mental illness. The influence of genetic factors on these diseases can be done by calcu
    Question

    Monozygotic and dizygotic twins are used to study the onset of mental illness. The influence of genetic factors on these diseases can be done by calculating the:

    A.

    Mutation rate

    B.

    Concordance rate

    C.

    Phenotype variation

    D.

    Environmental effect

    Correct option is B

    The correct answer is: (2) Concordance rate.

    Explanation:
    The concordance rate refers to the percentage of twin pairs in which both twins exhibit the same trait or disorder. This is especially useful in studies of mental illness, as it helps determine the genetic influence by comparing the occurrence of a disease in both monozygotic (identical) and dizygotic (fraternal) twins. Higher concordance rates in monozygotic twins compared to dizygotic twins suggest a stronger genetic component in the development of the disease.

    Information Booster:

    1. Monozygotic twins (identical twins) share 100% of their genetic material, while dizygotic twins (fraternal twins) share 50% of their genetic material.

    2. The concordance rate can be compared between monozygotic and dizygotic twins to assess the genetic contribution to a mental illness.

    3. A high concordance rate in monozygotic twins suggests that genetic factors play a significant role in the disease, whereas a lower concordance rate in dizygotic twins points to environmental or other factors.

    Additional Knowledge:

    • The mutation rate (option 1) refers to the frequency at which genetic mutations occur in a population, which is useful in evolutionary biology, but it does not directly measure genetic influence on diseases like mental illness.

    • Phenotype variation (option 3) refers to the variability in traits or disorders within a population, but it is not specific enough to directly assess the influence of genetic factors.

    • Environmental effects (option 4) play a role in the onset of mental illness, but the concordance rate is the most direct measure for studying the relative impact of genetics versus environment in twin studies.

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