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​Given below is a pedigree indicating a pattern on inheritance:​​Which one of the following options correctly describes the pattern of inheritance sho
Question

Given below is a pedigree indicating a pattern on inheritance:

Which one of the following options correctly describes the pattern of inheritance shown in the above pedigree?

A.

X-linked recessive

B.

Autosomal recessive

C.

X-linked dominant

D.

Autosomal dominant

Correct option is B

Explanation- 

From the pedigree chart -

Parents:
        Mother: Unaffected (white circle)
        Father: Unaffected (white square)
Children:
        Daughter: Affected (black circle)
        Son: Affected (black square)
Interpretation:
        Both parents are unaffected, yet both children (a son and a daughter) are affected. This rules out dominant inheritance, because if the trait were dominant, at least one parent would have to be affected to pass the trait.
This pattern fits recessive inheritance better, especially Autosomal Recessive Inheritance 
Both parents are unaffected carriers (heterozygous: Aa).
Each child has a 25% chance of being affected (aa).
Both sons and daughters can be equally affected — no sex bias.

Incorrect options-
Options a  –  X-linked Recessive
More common in males than females.
Affected daughter from unaffected parents is very unlikely, unless the father is affected — which he isn’t.

Option c -  X-linked Dominant
An affected daughter would require an affected parent — not the case here.
Again, both parents are unaffected, so this is ruled out.

Option d -  Autosomal Dominant
At least one parent must be affected to pass the dominant allele. Neither parent is affected here.

So, the correct answer is option b – Autosomal Recessive.







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