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Components of S-adenosyl methionine areChoose the correct answer from the options given below:
Question

Components of S-adenosyl methionine are

Choose the correct answer from the options given below:

A.

A and C only

B.

A and D only

C.

B and C only

D.

B and D only

Correct option is A

​S-Adenosyl methionine (SAM), is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase.

In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis. In eukaryotic cells, SAM serves as a regulator of a variety of processes including DNA, tRNA, and rRNA methylation; immune response; amino acid metabolism; transsulfuration; and more. In plants, SAM is crucial to the biosynthesis of ethylene, an important plant hormone and signaling molecule.

S-Adenosyl methionine consists of the adenosyl group attached to the sulfur of methionine, providing it with a positive charge.

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