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​Which one of the following bonds supports the three intertwined polypeptide strands in the triple helical structure of collagen?​
Question

Which one of the following bonds supports the three intertwined polypeptide strands in the triple helical structure of collagen?

A.

Disulfide bonds

B.

Hydrogen bonds

C.

Co-ordinate bonds

D.

Ionic bonds

Correct option is B

The correct answer is (b).

Hydrogen bonds play a critical role in stabilizing the triple helix structure of collagen. The three polypeptide strands in collagen form a helical structure where hydrogen bonds are formed between the amide hydrogen of one strand and the carbonyl oxygen of another, providing the necessary stability to the overall structure. These hydrogen bonds help maintain the integrity of the collagen molecule, ensuring that the strands remain intertwined and form a stable triple helix.

Incorrect options -

(a) is incorrect because ​Disulfide bonds (covalent bonds between cysteine residues) stabilize tertiary and quaternary structures in many proteins but are not involved in the collagen triple helix.

(c) is incorrect because Coordinate bonds usually involve metal ions (like Fe, Zn) bound to ligands, and are more common in metalloproteins, not collagen.

(d) is incorrect because Ionic bonds, formed between charged side chains, contribute to overall protein stability but are not the primary force in the triple helix of collagen.

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