Correct option is A
This experiment involves the transfer of two key immune components:
- Serum antibodies, which contains (such as neutralizing antibodies),
- T cells cell-mediated immunity, which contribute to .
The important details of the experiment:
- ancestral (Wuhan)cytotoxic T lymphocyte (CTL)Individuals vaccinated with the strain have good neutralizing antibody titres and activity against the Wuhan strain.
- recipient “A” recipient “B” The serum and T cells from these individuals are transferred to and respectively.
Recipient “A” will receive serum, which contains the neutralizing antibodies against the ancestral strain and, potentially, the Delta variant (since the vaccinated individuals are protected against the Delta variant, suggesting cross-reactivity of antibodies with this variant). These antibodies will help “A” combat infections with the ancestral strain and the Delta variant.
On the other hand, recipient “B” will receive only T cells, which are more specific to the Wuhan strain, and thus, may not provide full protection against the Delta or Omicron variants in the absence of the relevant antibodies. Therefore, “A” will be protected against both the ancestral strain and the Delta variant due to the presence of neutralizing antibodies.
- Omicron variant“A”: Since the vaccinated individuals' serum is not effective against the Omicron variant (as observed in the vaccinated individuals), will not be protected against the Omicron variant.
Therefore, Option 1 is correct.
Information Booster:
Neutralizing Antibodies: These antibodies are critical in preventing the virus from entering host cells and replicating.
Cytotoxic T Lymphocytes (CTLs): These cells are part of cell-mediated immunity and are essential in killing infected cells.
Omicron Variant: The Omicron variant has mutations in the spike protein that allow it to evade some immune responses, especially those based on neutralizing antibodies.
