Correct option is D
Explanation-
This pathway presents endogenous antigens (from within the cell, e.g., viral proteins) to CD8+ T cells.
Key components involved:
1. Proteasome (LMP2, LMP7): Degrades cytosolic proteins into peptides.
2. TAP1 & TAP2: Transport peptides from cytosol into the endoplasmic reticulum.
3. Invariant chain (Ii): NOT involved in MHC-I. It is specific to MHC class II presentation.
Options -
Option a : TAP1 and TAP2 proteins only
Partially correct (TAPs are essential), but missing proteasome subunits
Option b : Invariant chain (Ii)
Invariant chain is part of MHC class II presentation. This is incorrect
Option c : Proteasome-like subunits LMP2 and LMP7 only
Partially correct, but lacks TAP1/TAP2, which are essential for peptide transport
Option d : TAP1, TAP2 proteins and proteasome-like subunits LMP2, LMP7
Correct. This includes all key components of the MHC-I antigen processing pathway.
Final Answer: Option d is correct.


