Correct option is D
Explanation:
PONDR Score: The plot shows multiple peaks and valleys in the protein sequence, which suggests that the protein contains multiple regions of order and disorder.
The regions of disorder (low PONDR score) are present in multiple parts of the protein sequence, indicating the presence of flexible linkers between the structured (ordered) domains.
This type of pattern is commonly seen in multidomain proteins, where flexible linkers connect the different domains. This would explain the sequence's alternating regions of high and low PONDR scores.
Information Booster:
PONDR score is used to predict the disorder in a protein sequence.
Disordered regions are typically associated with flexibility, while ordered regions are structured and stable.
Flexible linkers are regions of disorder that connect functional protein domains.
Multidomain proteins often show patterns of disorder between domains, which is reflected in the PONDR score plot.
Additional Information:
Option 1: Incorrect, as the plot suggests multiple ordered regions connected by disordered regions rather than a single folded domain with terminal flexible tails.
Option 2: Incorrect, as the plot indicates the presence of multiple disordered regions rather than a uniform globular structure.
Option 3: Incorrect, as the PONDR plot shows multiple ordered regions, indicating the presence of ordered domains.
