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    ​Given below are two columns depicting structural features (Column X) and the DNA/RNA conformation (Column Y).​​Which one of the following options rep
    Question

    Given below are two columns depicting structural features (Column X) and the DNA/RNA conformation (Column Y).

    Which one of the following options represents all correct matches between Column X and Column Y?

    A.

    A-III, B-II, C-I, D-I

    B.

    A-I, B-III, C-II, D-I

    C.

    A-II, B-II, C-I, D-III

    D.

    A-III, B-I, C-III, D-II

    Correct option is A

    Explanation:

    • A. Left-handed

      • This describes Z-DNA, which is a left-handed helical structure.

      • Match: A → (iii) Z form

    • B. Number of base pairs per turn is 10

      • The common B-DNA has about 10 base pairs per turn.

      • Match: B → (ii) B form

    • C. The base pairs are off-centered

      • This is a feature of A-DNA, where the bases are tilted and displaced from the axis of the helix.

      • Match: C → (i) A form

    • D. RNA double helix

      • RNA double helices resemble the A-form rather than B or Z forms.

      • Match: D → (i) A form

    Information Booster:

    • B-DNA: The most common DNA conformation under physiological conditions, right-handed, with ~10 bp per turn.

    • A-DNA: A right-handed form of DNA, more compact with bases tilted and displaced from the helix axis. RNA double helices also resemble A-form.

    • Z-DNA: A left-handed DNA helix with a zigzag backbone. It forms under specific conditions and is less common.

    • RNA Double Helix: Due to the 2’-OH group on ribose, RNA favors the A-form conformation.


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