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Which one of the following statements about determination of ABO blood types is INCORRECT?​
Question

Which one of the following statements about determination of ABO blood types is INCORRECT?​

A.

ABO blood types are determined by three alleles of one gene.

B.

Four blood group phenotypes are produced by six genotypes.

C.

Parents with a type A and a type B could produce a type O child.

D.

Universal donors with O blood type do not carry antibodies against A and B.

Correct option is D

The correct answer is: (4) Universal donors with O blood type do not carry antibodies against A and B.

Explanation:
Universal blood donors with O type blood are often considered to be able to donate blood to any recipient because their red blood cells do not have A or B antigens. However, individuals with O type blood do carry antibodies against A and B antigens. These antibodies are present in the plasma and are important for recognizing and rejecting foreign antigens. This means that while O type blood can be donated to individuals of any blood group, O blood type donors do carry antibodies against A and B.

Information Booster:

  1. O type blood does not have A or B antigens on the surface of red blood cells, which makes it a universal donor for transfusions.

  2. The antibodies against A and B are present in the plasma of O-type individuals, but these do not affect the red blood cells during donation.

  3. For transfusions, O-negative blood is often considered the universal donor type because it lacks both A and B antigens and the Rh factor.

Additional Knowledge:

  • Statement 1 is correct. ABO blood types are indeed determined by three alleles (IA, IB, and i) of one gene.

  • Statement 2 is correct. Four blood group phenotypes (A, B, AB, O) are produced by six possible genotypes (IA IA, IA i, IB IB, IB i, IA IB, ii).

  • Statement 3 is correct. Parents with type A and type B blood can produce a type O child if both parents carry the i allele.

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