Correct option is B
The correct answer is (b).
Factor V is not a vitamin K-dependent blood clotting factor. Vitamin K is essential for the activation of several clotting factors, including Factor II (Prothrombin), Factor VII, Factor IX, and Factor X, as these factors require vitamin K to undergo a post-translational modification called gamma-carboxylation. This modification enables them to bind calcium ions and interact with phospholipid surfaces, crucial for coagulation. However, Factor V is not vitamin K-dependent and is part of the coagulation cascade, but its activation is independent of vitamin K.
Incorrect options-
Option (a) Factor II (Prothrombin): Vitamin K-dependent; crucial for thrombin generation.
Option (c) Factor IX: Vitamin K-dependent; involved in the intrinsic pathway.
Option (d) Factor X: Vitamin K-dependent; activated in both intrinsic and extrinsic pathways.
