Correct option is A
Explanation-
Statement analysis-
Statement A: CO₂ interacts with amino terminal nitrogens of Hb polypeptide chains - CORRECT
CO₂ forms carbamino compounds by reacting with the N-terminal amino groups of globin chains in hemoglobin, forming carbamates (e.g., carbaminohemoglobin).
Statement B: CO₂ interacts with carboxyl terminal carbons of Hb polypeptide chains - INCORRECT
CO₂ does not react with carboxyl terminal carbons. The reaction involves amino groups, not carboxyl ends.
Statement C: Carbamates help formation of salt bridges between α and β chains of Hb - CORRECT
Formation of carbamates adds a negative charge, which can stabilize deoxyhemoglobin (T-form) via additional salt bridges, aiding CO₂ transport and Bohr effect.
Statement D: Carbamates help formation of disulfide bridges between α and β chains of Hb - INCORRECT
Disulfide bridges form between cysteine residues, and carbamates do not participate in disulfide bond formation.
Correct combination: A and C
Final Answer: Option a
