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Which of the following is correct about use of bacterial strain in Avery, Macleod and McCarty experiment to establish DNA as genetic material?
Question

Which of the following is correct about use of bacterial strain in Avery, Macleod and McCarty experiment to establish DNA as genetic material?

A.

Live rough strain and live smooth strain of bacteria

B.

Live smooth strain and heat killed rough strain of bacteria

C.

Heat killed strains of both rough and smooth strains of bacteria

D.

Live rough strain and heat killed smooth strain of bacteria

Correct option is D

Correct Answer: (d)
Explanation:
Mixing heat-killed S strain with live R strain resulted in transformation of R into S type, proving DNA is the genetic material.
Information Booster:
S strain is virulent; R strain is non-virulent.
Heat inactivates cells but DNA remains intact.
DNA from S strain entered live R strain.
Transformed R cells gained capsule like S type.
This proved inheritance is controlled by DNA.
Additional Information (Incorrect Options):
(a) Both are alive; no transformation demonstration.
(b) Live S is already virulent; no proof gained.
(c) No live strain → transformation cannot occur.

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