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Which cell cycle phase is typically the shortest in mammalian cells?​
Question

Which cell cycle phase is typically the shortest in mammalian cells?

A.

​G0 phase

B.

G1 phase

C.

G2 phase

D.

Mitosis

Correct option is D

Mitosis is the shortest phase of the cell cycle, typically lasting around 1–2 hours in mammalian cells. It is a highly regulated process that involves the division of the nucleus and the cytoplasm to produce two daughter cells. In contrast, the G1 phase (gap 1) and G2 phase (gap 2) are longer because they involve growth and preparation for DNA replication or mitosis, while the S phase is dedicated to DNA synthesis.

Information Booster:
1. Mitosis consists of prophase, metaphase, anaphase, and telophase.
2. It is shorter than other phases because it primarily focuses on cell division.
3. The G1 phase is the longest in most cells as it involves significant growth and preparation.
4. The G2 phase ensures readiness for mitosis, including checking for DNA damage.
5. The duration of cell cycle phases can vary between different cell types and organisms. The G1 and G2 phases involve extensive cellular activities like growth and checkpoint mechanisms.
6. The G0 phase is not part of the active cycle but is crucial for maintaining non-dividing cells.

Additional Knowledge:

G0 phase (Option a):Cells in the G0 phase are in a quiescent state and not actively dividing. This phase can last indefinitely, depending on the cell type and its environmental signals.
G1 phase (Option b): This is the first gap phase where the cell grows, synthesizes proteins, and prepares for DNA replication. It is often the longest phase, especially in rapidly dividing cells.
G2 phase (Option c):This phase occurs after DNA replication and involves preparation for mitosis. The cell checks for DNA damage and ensures all replication is complete before division.
Mitosis (Option d): As the shortest phase, mitosis is highly dynamic and involves chromosomal segregation and cytokinesis. Despite its brevity, it is critical for genetic stability.

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