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    ​Column (A) lists enzymes involved in cell cycle and typical function in a particular cell cycle phase is listed in Column (B).​​Which one of the foll
    Question

    Column (A) lists enzymes involved in cell cycle and typical function in a particular cell cycle phase is listed in Column (B).

    Which one of the following options represents the correct match between column A and column B?

    A.

    A-(iv), B-(iii), C-(ii), D-(i)

    B.

    A-(iii), B-(iv), C-(ii), D-(i)

    C.

    A-(i), B-(ii), C-(iii), D-(iv)

    D.

    A-(ii), B-(i), C-(iv), D-(iii)

    Correct option is B

    Explanation-

    A. Cdk1 → (iii) Mitotic Entry
    Cdk1, in complex with Cyclin B, is crucial for entry into mitosis (G2/M transition). Triggers chromosome condensation, nuclear envelope breakdown, and spindle formation.

    B. APC/Ccdc20 → (iv) Anaphase Onset
    The Anaphase-Promoting Complex (APC/C) with Cdc20 as a co-activator marks securin and cyclins for degradation. This degradation allows separase to cleave cohesin, initiating anaphase.

    C. Cdk2 → (ii) S-phase Entry
    Cdk2 associates with Cyclin E to promote S-phase entry by initiating DNA replication.

    D. Aurora B → (i) Cytokinesis
    Aurora B is primarily involved in chromosome alignment and spindle assembly checkpoint, but more precisely associated with:

     Final Correct Matching:
    A → iii (Cdk1 → Mitotic entry)
    B → iv (APC/Cdc20 → Anaphase onset)
    C → ii (Cdk2 → S-phase entry)
    D → iv (Aurora B → Anaphase onset)

    So, the correct answer is option b - A-iii, B-iv, C-ii, D-i

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