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​Column (A) lists enzymes involved in cell cycle and typical function in a particular cell cycle phase is listed in Column (B).​​Which one of the foll
Question

Column (A) lists enzymes involved in cell cycle and typical function in a particular cell cycle phase is listed in Column (B).

Which one of the following options represents the correct match between column A and column B?

A.

A-(iv), B-(iii), C-(ii), D-(i)

B.

A-(iii), B-(iv), C-(ii), D-(i)

C.

A-(i), B-(ii), C-(iii), D-(iv)

D.

A-(ii), B-(i), C-(iv), D-(iii)

Correct option is B

Explanation-

A. Cdk1 → (iii) Mitotic Entry
Cdk1, in complex with Cyclin B, is crucial for entry into mitosis (G2/M transition). Triggers chromosome condensation, nuclear envelope breakdown, and spindle formation.

B. APC/Ccdc20 → (iv) Anaphase Onset
The Anaphase-Promoting Complex (APC/C) with Cdc20 as a co-activator marks securin and cyclins for degradation. This degradation allows separase to cleave cohesin, initiating anaphase.

C. Cdk2 → (ii) S-phase Entry
Cdk2 associates with Cyclin E to promote S-phase entry by initiating DNA replication.

D. Aurora B → (i) Cytokinesis
Aurora B is primarily involved in chromosome alignment and spindle assembly checkpoint, but more precisely associated with:

 Final Correct Matching:
A → iii (Cdk1 → Mitotic entry)
B → iv (APC/Cdc20 → Anaphase onset)
C → ii (Cdk2 → S-phase entry)
D → iv (Aurora B → Anaphase onset)

So, the correct answer is option b - A-iii, B-iv, C-ii, D-i

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