Correct option is D
Organophosphate insecticides are synthetic chemicals widely used to control insect pests in agriculture and public health. They function primarily by
inhibiting the enzyme acetylcholinesterase, which is essential for proper nervous system function in insects (and also in humans at toxic levels).
�� Historical Background:
· During
World War II,
Germany pioneered the development of
organophosphates.
· German chemists, particularly
Dr. Gerhard Schrader, were originally researching new chemical warfare agents.
· Schrader and his team at
IG Farben discovered organophosphate compounds with potent
neurotoxic effects.
· Some of these compounds, like
Tabun and Sarin, were classified as
nerve agents for warfare.
· However, milder derivatives were later adapted for
agricultural use as
substitutes for nicotine-based insecticides (e.g., nicotine sulfate), which were natural and costly.
· The commercial versions—like
parathion, malathion, and diazinon—were introduced later after the war.