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​Match the following:​​Which one of the following options represents all correct matches between Column X and Column Y?​
Question

Match the following:

Which one of the following options represents all correct matches between Column X and Column Y?

A.

A-III, B-IV, C-I, D-II

B.

A-IV, B-III, C-I, D-II

C.

A-IV, B-III, C-II, D-I

D.

A-III, B-IV, C-II, D-I

Correct option is A

The correct answer is (a).

  • DNA polymerase δ (A) is primarily responsible for synthesizing the lagging strand (iii).
  • DNA polymerase ε (B) is involved in synthesizing the leading strand (iv).
  • DNA polymerase β (C) is involved in base excision repair (i), where it plays a role in the repair of single-strand DNA damage.
  • DNA polymerase η (D) is involved in the thymine dimer bypass (ii), helping the cell to bypass the lesions caused by UV radiation-induced thymine dimers.

Incorrect options-

Option (b) incorrectly swaps the roles of δ and ε polymerases.

Option (c) misassigns all the functions.

Option (d) incorrectly assigns polymerase β to thymine dimer bypass instead of base excision repair.

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