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​Given below are a set of enzymes in Column A and enzyme activities in Column B.​​Choose the option that matches the contents of column A with that of
Question

Given below are a set of enzymes in Column A and enzyme activities in Column B.

Choose the option that matches the contents of column A with that of column B

A.

A-IV, B-III, C-II, D-I

B.

A-III, B-IV, C-II, D-I

C.

A-IV, B-III,IV,C-I, D-II

D.

A-III, B-III, IV, C-II, D-I

Correct option is A

Explanation-

(A) DNA Topoisomerase I → (iv) Single strand nicking
Topoisomerase I relieves supercoiling by making a single-strand nick, allowing rotation, then rejoining it.
(B) DNA Topoisomerase II → (iii) Double strand break and ligation
Topoisomerase II cuts both strands (double-strand break) to untangle DNA during replication and then re-ligates them.
(C) Polymerase ε (epsilon) → (ii) Leading strand synthesis
Polymerase epsilon is mainly responsible for leading strand DNA synthesis during replication in eukaryotes.
(D) Polymerase δ (delta) → (i) Synthesis of Okazaki fragments
Polymerase delta primarily carries out lagging strand synthesis (Okazaki fragments) in eukaryotic replication.

Correct Option:
Option a : A: iv; B: iii; C: ii; D: i

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