Glycosylated Hemoglobin reflects the average blood glucose level of the previous -

Correct option is D

Ans. (d) 3 months
Explanation:
Glycosylated Hemoglobin (HbA1c) is a key marker used in diabetes management. It reflects the average blood glucose levels over the past 2-3 months because:
· Red blood cells (RBCs) have a lifespan of ~120 days (3-4 months), and glucose binds to hemoglobin in RBCs irreversibly.
· The higher the blood glucose levels, the more glycosylation occurs, increasing HbA1c levels.
· Since RBCs do not all die at the same time, HbA1c gives a weighted average of blood glucose mainly over the last 8-12 weeks (~3 months).
Why is HbA1c Important?
· Used for diagnosing and monitoring diabetes.
· Gives a long-term picture of glucose control, unlike fasting or postprandial blood sugar, which show only short-term variations.
· Helps in assessing treatment efficacy and the risk of diabetes complications.
HbA1c Interpretation (Diabetes Diagnosis & Control Levels):