In Metabolic Acidosis, there is -

Correct option is C

Ans. (c) Excessive loss of bicarbonates
Explanation:
Metabolic Acidosis is a condition where there is an excess of acid or a loss of bicarbonate (HCO₃⁻) in the body, leading to a low blood pH (<7.35).
Causes of Metabolic Acidosis:
✅ Excessive loss of bicarbonates (HCO₃⁻) is the primary cause → Seen in:
· Severe diarrhea (loss of HCO₃⁻ in stool).
· Renal failure (impaired bicarbonate reabsorption).
· Diabetic ketoacidosis (DKA) (acid buildup).
· Lactic acidosis (due to hypoxia or shock).
Why are the other options incorrect?
1. Excessive loss of sodium ❌ (Incorrect Choice)
· Sodium (Na⁺) imbalance may occur in some metabolic disorders, but it does not directly cause metabolic acidosis.
2. Excessive loss of potassium ❌ (Incorrect Choice)
· Metabolic acidosis is associated with hyperkalemia (high K⁺), not excessive loss.
· Acidic blood shifts H⁺ ions into cells and pushes K⁺ into the bloodstream.
3. Decrease in chloride levels ❌ (Incorrect Choice)
· Metabolic acidosis is usually associated with normal or increased chloride levels (Hyperchloremic Acidosis).
· Decreased chloride (hypochloremia) is more common in metabolic alkalosis.