Which of the following drugs is a Glycoside?

Correct option is B

Ans. (b) Digoxin
Explanation:
Glycosides are compounds that consist of a sugar molecule attached to a non-sugar component (aglycone).
✅ Digoxin is a cardiac glycoside derived from Digitalis (Foxglove plant), used to treat heart failure and atrial fibrillation.
Mechanism of Action of Digoxin:
· Inhibits Na⁺/K⁺-ATPase, leading to increased intracellular calcium, which enhances cardiac contractility ( positive inotropic effect).
· Slows heart rate (negative chronotropic effect) by increasing vagal tone.
Why are the other options incorrect?
1. Serpasil (Reserpine) → (Incorrect Choice) ❌
· An antihypertensive drug, not a glycoside.
· Depletes catecholamines (dopamine, norepinephrine, serotonin) to reduce blood pressure.
2. Lasix (Furosemide) → (Incorrect Choice) ❌
· A loop diuretic, not a glycoside.
· Inhibits Na⁺-K⁺-2Cl⁻ symporter in the loop of Henle, increasing urine output.
3. Morphine → (Incorrect Choice) ❌
· An opioid analgesic, not a glycoside.
· Binds to μ-opioid receptors, providing pain relief.