Column X lists proteins that play a role in mediating DNA recombination processes and Column Y lists the possible functions of these proteins.

Column X Proteins	Column Y Functions
A. Rad51	i. Assembly of strand exchange proteins
B. Spo11	ii. Resection of ends of DNA strands at double strand break sites to create single strand overhangs
C. Rad52 and Rad59	iii. Causes double strand breaks in meiosis
D. MRX/N complex	iv. Strand invasion

Which one of the following options represents all correct matches between Column X and Column Y?

Correct option is C

Analysis of Each Protein and Its Function:

1. Rad51 (A):

   • Function: Rad51 is crucial in strand invasion, a process where it aids in the homologous recombination mechanism. It facilitates the invasion of a single strand into a homologous DNA molecule, making it essential for the repair of double-strand breaks in DNA.

   • Correct Match: A matches with iv (Strand invasion).

2. Spo11 (B):

   • Function: Spo11 is involved in causing double strand breaks during meiosis. These breaks are essential for initiating recombination during meiosis, allowing homologous chromosomes to exchange genetic material.

   • Correct Match: B matches with iii (Causes double strand breaks in meiosis).

3. Rad52 and Rad59 (C):

   • Function: Rad52 and Rad59 are involved in the assembly of strand exchange proteins during homologous recombination, helping in the repair of DNA by facilitating strand exchange.

   • Correct Match: C matches with i (Assembly of strand exchange proteins).

4. MRX/N complex (D):

   • Function: The MRX/N complex helps in resequencing of the ends of DNA strands at double strand break sites, creating single-strand overhangs. This resection is critical for the subsequent recombination and repair processes.

   • Correct Match: D matches with ii (Resection of ends of DNA strands at double strand break sites to create single strand overhangs).

Correct Answer:

• A matches with iv (Strand invasion).

• B matches with iii (Causes double strand breaks in meiosis).

• C matches with i (Assembly of strand exchange proteins).

• D matches with ii (Resection of ends of DNA strands at double strand break sites to create single strand overhangs).