Which one of the following options represents all correct matches between

Column X: Microorganism	Column Y : Host Receptor
A. Influenza virus	i. N – acetylglucosamine
B. Entamoeba histolytica	ii. CD44
C. Streptococcus pyogenes	iii. Sialic acid residues of glycoproteins and glycolipids
D. Human immunodeficiency virus	iv. CD4

Column X and Column Y?
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​Which of the following options represents the correct combinations?​

Correct option is D

Explanation:

1. A (Influenza virus) binds to sialic acid residues of glycoproteins and glycolipids (iii). Influenza virus uses the sialic acid residue present on the surface of glycoproteins and glycolipids for attachment to host cells. This is a well-known mechanism for viral entry.

2. B (Entamoeba histolytica) attaches to N-acetylglucosamine (i). This amoeba uses N-acetylglucosamine for adhesion to the host tissues during the infection process. It recognizes this sugar molecule on the host cell surface.

3. C (Streptococcus pyogenes) interacts with CD44 (ii). This bacterium uses CD44 as a receptor to bind and enter host cells, which is important for establishing infection.

4. D (Human immunodeficiency virus) targets CD4 (iv) on immune cells. CD4 is the primary receptor that HIV uses to enter T-helper cells, a key process for the virus's replication and infection.

Information Booster:

• Influenza virus binds to sialic acid residues present on glycoproteins and glycolipids on host cell surfaces, facilitating viral entry.
• Entamoeba histolytica recognizes N-acetylglucosamine, a component of glycoproteins, to bind to and infect human tissues.
• Streptococcus pyogenes specifically interacts with CD44, a cell surface glycoprotein, for adhesion and infection.
• HIV binds to CD4 receptors on T-helper cells, a crucial step for viral entry and immune system impairment.