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Which one of the following is considered as a renal hormone?
Question

Which one of the following is considered as a renal hormone?

A.

Megalin

B.

Cubilin

C.

Renalase

D.

Uroguanylin

Correct option is C

Renalase is indeed considered a renal hormone. It is an enzyme produced by the kidneys and secreted into the bloodstream. Renalase plays a key role in the regulation of blood pressure by catabolizing catecholamines such as dopamine, epinephrine, and norepinephrine, thus influencing sympathetic tone. In addition to its enzymatic role, renalase is recognized for its effects on cardiovascular regulation, particularly in hypertension and kidney function.

Renalase is produced by the kidneys, and its secretion is considered an important aspect of renal endocrine regulation, which fits the description of a renal hormone.

Additional Information:

  • (a) Megalin: Incorrect — Megalin is a receptor involved in endocytosis of filtered proteins in the kidneys, not a hormone.
  • (b) Cubilin: Incorrect — Cubilin is a receptor involved in the reabsorption of proteins in the kidneys, not a hormone.
  • (d) Uroguanylin: Incorrect — Uroguanylin is a peptide hormone that acts in the kidneys, but it is not the most widely recognized renal hormone compared to renalase.

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