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The following statements were proposed by a researcher on the characteristic features of stretch receptors in atria and the effect of these receptors’
Question

The following statements were proposed by a researcher on the characteristic features of stretch receptors in atria and the effect of these receptors’ activity on blood pressure regulation:

A. The activity of type A receptors is increased by bursts of impulses during atrial systole
B. The activity of type B receptors is increased by bursts of impulses at the time of peak atrial filling during late diastole of atria
C. The discharge of type B atrial receptors is increased when venous return is increased
D. The activity of type B atrial receptors is increased by positive pressure breathing
E. The increased activity of most of the atrial receptors initiates reflex circulatory adjustment by increasing blood pressure
F. The heart rate is decreased reflexly by the increased activity of atrial receptors

Choose all CORRECT statements from the following options:

A.

C, D and E

B.

D, E and F

C.

A, B ,C and D

D.

B and C

Correct option is C

Explanation-

Type A receptors: Activated during atrial systole (when atria contract).
Type B receptors: Activated during atrial filling (late diastole).
Both are low-pressure baroreceptors that monitor venous return and blood volume. Their stimulation generally causes reflex tachycardia and diuresis (Bainbridge reflex), not an increase in blood pressure.

Statement A - The activity of type A receptors is increased by burst of impulses during atrial systole - CORRECT
Type A receptors fire during atrial contraction, i.e., systole.
Statement B - The activity of type B receptors is increased by burst of impulses at the time of peak atrial filling during late diastole of atria  - CORRECT
Type B receptors are activated by stretch due to venous return in late diastole.
Statement C -  The discharge of type B atrial receptors is increased when venous return is increased  - CORRECT
More venous return = more atrial filling, leading to greater stretch and increased discharge of type B receptors.
Statement D -  The activity of type B atrial receptors is increased by positive pressure breathing   - CORRECT
Positive pressure breathing increases intrathoracic pressure, influencing venous return and atrial stretch, which can stimulate B receptors.
Statement E -  The increased activity of most of the atrial receptors initiates reflex circulatory adjustment by increasing blood pressure  - INCORRECT
Their stimulation leads to vasodilation, natriuresis, and diuresis (not increased BP). They reduce blood volume and pressure, not increase it.
Statement F -  The heart rate is decreased reflexly by the increased activity of atrial receptors - INCORRECT
This is opposite of the Bainbridge reflex. Increased atrial receptor activity → reflex increase in HR (not decrease).

Final Answer:
Correct statements: A, B, C, and D
So, the most appropriate option is Option c - A, B and C

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