Non-pitting edema is seen in which of the following diseases?

Correct option is A

Ans. (a) Filariasis
Explanation:
Edema is an abnormal accumulation of fluid in the tissues. It is classified into pitting edema and non-pitting edema based on how it responds to pressure.
Non-Pitting Edema:
· Definition: When pressure is applied to the swollen area, no indentation remains after releasing the pressure.
· Cause: Due to lymphatic obstruction, leading to protein-rich fluid accumulation (lymphedema) in the tissues.
Diseases causing Non-Pitting Edema:
✅ Filariasis (Lymphatic Filariasis) → Correct Answer
· Cause: Wuchereria bancrofti (most common), Brugia malayi
· Mechanism:
· Parasitic infection blocks lymphatic drainage, leading to chronic lymphedema (elephantiasis).
· The swelling becomes fibrotic and hard, characteristic of non-pitting edema.
· Common Sites: Legs, scrotum, arms, breasts.
Why are the other options incorrect?
1. Congestive Heart Failure (CHF) → (Incorrect Choice)
· Causes pitting edema due to increased hydrostatic pressure, leading to fluid accumulation in dependent areas (legs, ankles, lungs - pulmonary edema).
2. Nephrotic Syndrome → (Incorrect Choice)
· Causes pitting edema due to hypoalbuminemia (loss of albumin in urine), reducing oncotic pressure and leading to fluid leakage into tissues.
3. Liver Cirrhosis → (Incorrect Choice)
· Causes pitting edema due to low albumin levels (hypoalbuminemia) and portal hypertension, leading to ascites and peripheral edema.