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    ​Match the following ribose sugar pucker in nucleic acids (labeled A, B, C, D) with their corresponding conformational states. The black circle denote
    Question

    Match the following ribose sugar pucker in nucleic acids (labeled A, B, C, D) with their corresponding conformational states. The black circle denotes the base of the nucleotide.

    A.

    A – C2’–exo; B – O4’–exo; C – C3’–endo; D – O4’–endo

    B.

    A – C2’–endo; B – O4’–endo; C – C3’–endo; D – O4’–exo

    C.

    A – C2’–endo; B – O4’–exo; C – C3’–endo; D – O4’–exo

    D.

    A – C2’–exo; B – O4’–endo; C – C3’–exo; D – O4’–endo

    Correct option is B

    EXPLANATION-

    In ribose puckers, atoms can be classified as endo (above the ring plane) or exo (below the ring plane).

    Structure A - C2′ is above the plane of the ribose ring.
    This is a C2′-endo conformation.

    Structure B - O4′ is above the plane of the ribose ring.
    This is a O4′-endo conformation.

    Structure C - C3′ is above the plane.
    This is a C3′-endo conformation.

    Structure D - O4′ is below the plane, hence exo.
    This is a O4′-exo conformation.

    So, the correct option is (b) - A – C2’–endo; B – O4’–endo; C – C3’–endo; D – O4’–exo

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