Injection Morphine is given intrathecal during a procedure for pain relief. After the procedure,
which of the following analgesics should not be administered?

Correct option is D

· Paracetamol: Paracetamol is a safe analgesic and antipyretic that can be used for mild to moderate pain relief without significant interaction with intrathecal morphine.
· Diclofenac: Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), can be used alongside intrathecal morphine for additional pain relief as it acts via a different mechanism.
· Tramadol: Tramadol is a weak opioid analgesic and can be used cautiously with intrathecal morphine; however, it does not pose a significant interaction risk.
· Fentanyl: Fentanyl is a potent opioid analgesic, and its administration after intrathecal morphine may increase the risk of severe respiratory depression due to additive opioid effects. This makes fentanyl the analgesic that should be avoided in this scenario.
Additional Information:
· Tramadol also a synthetic opioid. But, fentanyl is proved to be superior to tramadol.
· Paracetamol can be administered in post operative pain relief.
· Diclofenac is avoided in case of patient with asthma.