Identify an autosomal dominant disorder from the following.

Correct option is C

Huntington’s disease is a classic example of an autosomal dominant genetic disorder. This means only one copy of the defective gene, inherited from either parent, is enough to cause the disease. It affects the nervous system, leading to progressive neurodegeneration, movement disorders, psychiatric symptoms, and cognitive decline. Symptoms usually appear between ages 30 and 50.
Explanation of options: (a) Cystic fibrosis – This is an autosomal recessive disorder, requiring two defective CFTR gene copies for the condition to manifest. (b) Sickle cell anaemia – Also an autosomal recessive condition, it requires both alleles to be mutated for the disease to be expressed. (c) Huntington’s disease – This is the correct answer. It follows an autosomal dominant inheritance pattern and shows anticipation in successive generations. (d) Tay-Sachs disease – It is an autosomal recessive disorder caused by a deficiency of the enzyme hexosaminidase A, leading to neurodegeneration.