Correct option is D
The most common and chief cause of pulmonary embolism (PE) is venous thrombosis, particularly deep vein thrombosis (DVT) originating from the deep veins of the lower extremities. When a part of this thrombus dislodges, it travels through the venous system to the right side of the heart and then into the pulmonary arteries, causing a pulmonary embolism.
This condition is part of the venous thromboembolism (VTE) spectrum, which includes:
- Deep vein thrombosis (DVT)
- Pulmonary embolism (PE)
Major risk factors for venous thrombosis include:
- Prolonged immobility
- Surgery (especially orthopedic)
- Cancer
- Oral contraceptives
- Hypercoagulable states
Explanation of Each Option:
- (a) Fat emboli –
Occurs after long bone fractures, especially femur, but is a rare cause of pulmonary embolism. Not the chief or common cause. - (b) Air emboli –
Seen in cases like central line insertion or trauma, but it is uncommon and not the primary cause of PE. - (c) Septic emboli –
Arise from infected thrombi, such as in endocarditis, and can cause embolism, but these are less common and secondary causes. - (d) Venous thrombosis –
This is the leading and most frequent cause of pulmonary embolism, especially from lower limb DVT.