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A newborn presents with progressive hydrocephalus. MRI shows cystic dilation of 4th ventricle due to blockage of foramina of Luschka and Magendie. Dia
Question

A newborn presents with progressive hydrocephalus. MRI shows cystic dilation of 4th ventricle due to blockage of foramina of Luschka and Magendie. Diagnosis?

A.

Arnold–Chiari malformation

B.

Holoprosencephaly

C.

Dandy–Walker syndrome

D.

Aqueductal stenosis

Correct option is C

Dandy–Walker malformation involves agenesis of cerebellar vermis, cystic dilatation of 4th ventricle, and hydrocephalus due to blocked foramina of Luschka and Magendie.
Explanation of options: (a) ✘ Arnold–Chiari is downward herniation of cerebellum, not cystic 4th ventricle. (b) ✘ Holoprosencephaly = failure of forebrain division, not posterior fossa anomaly. (c) ✔ Correct; classic triad = hydrocephalus, enlarged posterior fossa, 4th ventricle cyst. (d) ✘ Aqueductal stenosis blocks 3rd–4th ventricle pathway, not 4th ventricle exit.

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