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    After BCG vaccination, when is the local skin response (scar formation) usually seen and considered as evidence of effective vaccination?
    Question

    After BCG vaccination, when is the local skin response (scar formation) usually seen and considered as evidence of effective vaccination?

    A.

    1–2 weeks

    B.

    4–6 weeks

    C.

    8–10 weeks

    D.

    12–16 weeks

    Correct option is B

    BCG vaccination produces a local nodule → ulcer → scar. The typical scar develops in 4–6 weeks, considered as evidence of successful vaccination.
    Explanation of options: (a) ✘ At 1–2 weeks, only small induration is seen, not scar. (b) ✔ Correct; scar forms around 4–6 weeks. (c) ✘ At 8–10 weeks, scar may persist, but response is expected earlier. (d) ✘ 12–16 weeks is too late, delayed healing is abnormal.

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