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A human subject can voluntarily inhibit respiration for some time but the subject feels irresistible urge to resume breathing after a while at a point
Question

A human subject can voluntarily inhibit respiration for some time but the subject feels irresistible urge to resume breathing after a while at a point which is called the breaking point. The characteristic features of breaking point are suggested in the following statements:

A. The breaking point is shorter in subjects after removal of carotid bodies compared to when they have intact carotid bodies.
B. The breaking point is prolonged if the subject breathes 100% oxygen before breath holding.
C. When the subject hyperventilates with room air before breath holding, the breaking point is delayed compared to when the subject breathes normally before breath holding.
D. The breaking point can be reduced in a subject by making respiratory movements behind a closed glottis.
E. The breaking point is shorter when the subject is told during breath holding that her/his performance is very good compared to a situation when she/he is not told so.
Choose both the correct statements from the following options:

A.

A and B

B.

B and C

C.

C and D

D.

D and E

Correct option is B

Explanation-

Statement A The breaking point is shorter in subjects after removal of carotid bodies compared to when they have intact carotid bodies   -  Incorrect
Carotid bodies are peripheral chemoreceptors sensitive to low O₂ and high CO₂.
Removal reduces the sensitivity to hypoxia and hypercapnia, meaning the drive to breathe is weakened, and the breaking point is delayed, not shortened.

Statement B -  The breaking point is prolonged if the subject breathes 100% oxygen before breath holding    -   Correct
Breathing 100% oxygen saturates hemoglobin and delays the fall in arterial O₂, postponing the activation of chemoreceptors.
Therefore, breaking point is prolonged.

Statement C -  When the subject hyperventilates with room air before breath holding, the breaking point is delayed compared to when the subject breathes normally before breath holding    -    Correct
Hyperventilation lowers CO₂ levels in the blood (hypocapnia), which delays the buildup of CO₂—the main trigger for the urge to breathe. This prolongs the breaking point.

Statement D-    The breaking point can be reduced in a subject by making respiratory movements behind a closed glottis   -    Incorrect.
These are called "false breathing movements" (e.g., Valsalva maneuvers), which may provide psychological relief but do not physiologically lower CO₂. They do not significantly reduce the breaking point.

Statement E -  The breaking point is shorter when the subject is told during breath holding that her/his performance is very good compared to a situation when she/he is not told so     -  Incorrect.
Positive encouragement may improve mental endurance and delay the breaking point. This statement is opposite of the expected outcome.

So, the correct answers is option b -  B and C.

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