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Given below are a few hormones (Column X) and their specific inhibitors (Column Y). Column X A. Growth hormone B. Progestogens C. Parathormon
Question

Given below are a few hormones (Column X) and their specific inhibitors (Column Y).
Column X
A. Growth hormone
B. Progestogens
C. Parathormone
D. Follicle-stimulating hormone
Column Y
i. Mifepristone
ii. Inhibin B
iii. Somatostatin
iv. High calcium levels
Which one of the following combinations correctly matches the hormones with their inhibitors?

A.

A–i; B–ii; C–iv; D–iii

B.

A–iii; B–i; C–iv; D–ii

C.

A–iv; B–ii; C–iii; D–i

D.

A–iii; B–iv; C–i; D–ii

Correct option is B

Correct Answer:
(b) A–iii; B–i; C–iv; D–ii
Explanation:
Growth hormone secretion is inhibited by somatostatin (A–iii).
Mifepristone is a progesterone receptor antagonist and inhibits the action of progestogens (B–i).
Parathormone (PTH) secretion is suppressed by high calcium levels via negative feedback (C–iv).
Inhibin B specifically inhibits follicle-stimulating hormone (FSH) secretion from the anterior pituitary (D–ii).
Information Booster :
· Hormone secretion is commonly regulated by feedback inhibition.
· Somatostatin is a broad inhibitory hormone affecting GH and TSH.
· Inhibin B provides gonad-specific regulation of FSH levels.
· Calcium homeostasis tightly controls parathormone release.
Additional Information (Incorrect Options):
A–i / A–iv: Growth hormone is not directly inhibited by mifepristone or calcium.
B–ii / B–iv: Progestogens are not inhibited by inhibin or calcium levels.
C–i / C–iii: Parathormone is not inhibited by steroid antagonists or somatostatin.
D–i / D–iii: FSH is not inhibited by mifepristone or somatostatin directly.

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