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Which one of the following molecules is transported into enterocytes from intestinal lumen by GLUT5?
Question

Which one of the following molecules is transported into enterocytes from intestinal lumen by GLUT5?

A.

Glucose

B.

Galactose

C.

Fructose

D.

Lactose

Correct option is A

Correct Answer: c) Fructose

Explanation:

GLUT5 is a facilitated diffusion transporter specifically responsible for the uptake of fructose from the intestinal lumen into enterocytes (intestinal absorptive cells).
It operates independently of sodium ions (Na⁺) and allows fructose to move along its concentration gradient.

Information Booster:

Glucose and galactose are transported via the SGLT1 (sodium-glucose linked transporter 1) using secondary active transport (Na⁺ dependent).

Once inside the enterocyte, all monosaccharides (glucose, galactose, fructose) exit into the bloodstream through the GLUT2 transporter located on the basolateral membrane.

Lactose, being a disaccharide, is not directly transported; it must first be hydrolyzed by lactase enzyme into glucose and galactose before absorption.

Additional Knowledge (Incorrect Options Explained):

a) Glucose: Transported by SGLT1, not GLUT5.

b) Galactose: Also transported by SGLT1, not GLUT5.

d) Lactose: Too large for transport; must be digested first.

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