Correct option is D
An endocrine gland is a structure that secretes hormones directly into the bloodstream.
Pituitary gland – a major endocrine gland (“master gland”)
Parathyroid gland – secretes parathyroid hormone
Pancreas – has an endocrine part (Islets of Langerhans) that secretes insulin and glucagon
The hypothalamus, although it produces releasing and inhibiting hormones, is primarily a part of the brain (neuroendocrine structure) and not classified as a pure endocrine gland.
Therefore, the correct answer is Hypothalamus.