Correct option is D
In erythroblastosis fetalis, excessive breakdown of fetal red blood cells leads to severe hyperbilirubinemia. If untreated, high bilirubin levels can cross the blood-brain barrier and cause kernicterus, a form of permanent brain damage.
Explanation of each option: • (a) Liver – Though bilirubin is processed in the liver, the liver is not the primary organ at risk from high bilirubin in neonates. • (b) Lungs – Lung function is not directly compromised by hyperbilirubinemia in erythroblastosis fetalis. • (c) Kidneys – Kidneys are not primarily affected by elevated bilirubin unless secondary complications occur. • (d) Brain – Correct. Excess unconjugated bilirubin is neurotoxic and can lead to kernicterus, hence exchange transfusion is done to protect the brain.