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    Which of the following is a rare disease in which tumours cause the stomach to produce too much acid, resulting in peptic ulcers?
    Question

    Which of the following is a rare disease in which tumours cause the stomach to produce too much acid, resulting in peptic ulcers?

    A.

    Boerhaave syndrome

    B.

    Zollinger–Ellison syndrome

    C.

    Mallory-Weiss syndrome

    D.

    Abdominal compartment syndrome

    Correct option is B


    Zollinger–Ellison syndrome is a rare condition where tumours (gastrinomas) cause excessive production of stomach acid, leading to peptic ulcers. The tumours are usually found in the pancreas or the duodenum.
    Explanation of options: (a) ✘ Incorrect. Boerhaave syndrome refers to the spontaneous rupture of the esophagus, often caused by severe vomiting, not due to excess stomach acid production. (b) ✔ Correct. Zollinger–Ellison syndrome is characterized by gastrin-secreting tumours, leading to excess stomach acid and peptic ulcers. (c) ✘ Incorrect. Mallory-Weiss syndrome involves tears at the junction of the stomach and esophagus, often due to forceful vomiting, not excessive stomach acid production. (d) ✘ Incorrect. Abdominal compartment syndrome refers to increased pressure within the abdomen, which can lead to organ dysfunction, not to excessive acid production in the stomach.

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