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What is the drug of choice for leprosy?
Question

What is the drug of choice for leprosy?

A.

Chloroquine

B.

Primaquine

C.

Dapsone

D.

Rifampicin

Correct option is C

Dapsone is the primary drug used in the treatment of leprosy. It is a bacteriostatic agent that works by inhibiting folic acid synthesis in Mycobacterium leprae. It is usually given as part of a multidrug therapy regimen along with rifampicin and clofazimine to prevent resistance. Early and continued treatment helps prevent deformities and transmission.
Explanation of options: (a) ✘ Chloroquine – Used for malaria, not effective against Mycobacterium leprae. (b) ✘ Primaquine – Also an antimalarial, specifically for liver stages of malaria. (c) ✔ Dapsone – Mainstay treatment for leprosy due to its bacteriostatic action. (d) ✘ Rifampicin – Also used in leprosy, but not the sole drug of choice.

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