Correct option is C
Explanation
Vaccines are biological products that are sensitive to temperature changes. To maintain their potency, safety, and effectiveness, most vaccines must be stored in the cold chain at a temperature between 2°C and 8°C. This temperature range prevents vaccines from being damaged by excessive heat or freezing. If vaccines are exposed to temperatures outside this range, they may lose their ability to produce immunity, even though they may appear normal.
The cold chain includes refrigerators, cold boxes, vaccine carriers, and temperature-monitoring devices that ensure vaccines remain within the recommended range from the manufacturer to the point of administration. Some vaccines, such as DPT, Hepatitis B, Pentavalent, and TT, are particularly sensitive to freezing, while others may be damaged by heat. Therefore, maintaining a storage temperature of 2–8°C is essential for successful immunization programs.