Correct option is D
Explanation:
The tri-snRNP particle is a complex involved in the process of splicing during RNA processing. It consists of the U4, U6, and U5 snRNPs (small nuclear ribonucleoproteins), which are essential for the splicing reaction carried out by the spliceosome. These snRNPs are involved in the catalysis of the excision of introns from precursor mRNA (pre-mRNA). The U4 and U6 snRNPs play a key role in the formation of the spliceosome's active site, while U5 assists in the catalysis of the ligation of exons after the intron is removed.
Information Booster:
The tri-snRNP complex is crucial for the assembly of the spliceosome, where the U4, U6, and U5 snRNPs work together to carry out the splicing of introns from the mRNA transcript.
U4 and U6 snRNPs are involved in the formation of the spliceosome, with U6 playing a central role in catalyzing the splicing reaction.
U5 snRNP is also essential in the splicing process and ensures that the exons are ligated properly after the introns are excised.
The tri-snRNP particle is formed in the nucleus and is recruited to the splice sites of the pre-mRNA for the splicing process.
The splicing process is essential for the maturation of eukaryotic mRNA, ensuring that non-coding introns are removed and the coding regions (exons) are joined together.
Additional Knowledge:
U1, U4, and U3 snRNPs (option 1) are not components of the tri-snRNP particle. U1 snRNP is involved in recognizing the 5' splice site, but it is not part of the tri-snRNP.
U2, U4, and U3 snRNPs (option 2) do not make up the tri-snRNP. U2 snRNP is involved in recognizing the branch point during splicing but does not form the tri-snRNP.
U3, U6, and U5 snRNPs (option 3) is incorrect, as U3 is not involved in the tri-snRNP particle; rather, U4, U6, and U5 are the key components involved in splicing.
