The most sensitive test for the diagnosis of dengue fever is -

Correct option is C

Sol. Polymerase Chain Reaction (PCR) is the most sensitive test for the early diagnosis of dengue fever. It detects the viral RNA in the patient's blood, allowing for confirmation of infection during the acute phase, typically within the first five days of symptom onset. PCR offers high specificity and sensitivity, making it a valuable tool in early diagnosis and management of dengue.
Explanation of Each Option:
· NS1 antigen test: Incorrect; detects the non-structural protein 1 of the dengue virus and is useful in early diagnosis but is less sensitive than PCR.
· IgM ELISA: Incorrect; detects IgM antibodies against dengue virus, indicating a recent infection, but antibodies may not be present in the early stages.
· PCR: Correct answer; identifies viral RNA with high sensitivity during the early phase of infection.
· Tourniquet test: Incorrect; a clinical test that indicates capillary fragility but is not specific or sensitive for dengue diagnosis.