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The levels of which one of the following parameters of blood are measured to check cardiac damage?
Question

The levels of which one of the following parameters of blood are measured to check cardiac damage?

A.

Creatine

B.

Creatine kinase

C.

Peroxidase

D.

Urea

Correct option is B

Correct Answer:
 Option (b) — Creatine kinase

Explanation:
Creatine kinase (CK), also known as creatine phosphokinase (CPK), is an enzyme found primarily in heart, skeletal muscle, and brain tissues.
When cardiac muscle cells are damaged (as in myocardial infarction), CK levels—particularly the CK-MB isoenzyme—increase in the blood.
Hence, measuring serum CK-MB activity is a standard diagnostic test for cardiac damage.

Information Booster:
-Creatine kinase (CK) Isoenzymes:
-CK-MM: Found in skeletal muscle
-CK-BB: Found in brain
-CK-MB: Found in cardiac muscle (marker for myocardial infarction)

Other cardiac markers:
-Troponin I and T – most specific and sensitive indicators
-Lactate dehydrogenase (LDH-1) – older, secondary marker

Additional Knowledge (Incorrect Options Explained):
(a) Creatine: A metabolite, not a marker of cardiac injury.
(c) Peroxidase: An enzyme in various cells; not cardiac-specific.
(d) Urea: Reflects kidney function, not cardiac damage.

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