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    The first line of drugs for treatment of tuberculosis are?
    Question

    The first line of drugs for treatment of tuberculosis are?

    A.

    Isoniazid, Rifampicin, Pyrazinamide, Ethambutol and Streptomycin

    B.

    Rifampicin, NH, streptomycin, PAS and Amikacin

    C.

    Rifampicin, NH, streptomycin, Kanamycin and Ethambutol

    D.

    NH, Streptomycin, Kanamycin and PAS

    Correct option is A


    Sol. First-line anti-TB drugs include Isoniazid (INH), Rifampicin, Pyrazinamide, Ethambutol, and Streptomycin, as per WHO and NTEP guidelines. They are effective against drug-sensitive TB and are less toxic than second-line drugs.
    Explanation of each option:
    · (a) INH, Rifampicin, Pyrazinamide, Ethambutol, Streptomycin – Correct standard first-line regimen.
    · (b) PAS and Amikacin – These are second-line drugs, used in MDR-TB cases, not in first-line.
    · (c) Kanamycin – Injectable second-line drug; not used routinely in new TB patients.
    · (d) PAS and Kanamycin – Both are for resistant TB cases, not first-line standard regimen.

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