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    Islets of Langerhans are present in–
    Question

    Islets of Langerhans are present in–

    A.

    Brain

    B.

    Stomach

    C.

    Ovary

    D.

    Pancreas

    Correct option is D


    Sol. The Islets of Langerhans are clusters of endocrine cells located in the pancreas. They play a key role in glucose metabolism by secreting hormones like insulin (β-cells), glucagon (α-cells), and somatostatin (δ-cells). Dysfunction in these cells is the underlying cause of diabetes mellitus, making them clinically very significant.
    Explanation of each option:
    · (a) Brain – Though the brain is affected by glucose levels, it does not produce insulin or glucagon. No islets of Langerhans are found here.
    · (b) Stomach – Secretes digestive enzymes and gastric hormones like gastrin, but lacks endocrine cells responsible for glucose regulation.
    · (c) Ovary – Involved in reproductive hormone production like estrogen and progesterone, not metabolic hormones like insulin.
    · (d) Pancreas – Correct Answer. It contains both exocrine cells (digestive enzymes) and endocrine Islets of Langerhans, which are vital for blood glucose regulation.

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