Correct option is B
Calcitonin is a peptide hormone synthesized by the C-cells of the thyroid gland. It consists of 32 amino acids and is responsible for lowering calcium levels in the blood by inhibiting osteoclast activity, which reduces bone resorption. The 32 amino acids form its functional and active structure.
Information Booster:
- Calcitonin consists of 32 amino acids.
- The hormone is crucial for regulating calcium homeostasis and preventing hypercalcemia.
- C-cells are the cells in the thyroid gland responsible for the synthesis of calcitonin.
- It works in opposition to parathyroid hormone (PTH), which increases blood calcium levels.
- The structure of calcitonin is characterized by a signal peptide that is cleaved during hormone secretion.
- Therapeutic use: Calcitonin is used in treating diseases like osteoporosis due to its bone-preserving effects.
- It reduces osteoclast activity, leading to a decrease in bone resorption.
Additional Information:
- 42 amino acids: This number is often associated with parathyroid hormone, which regulates calcium levels in the opposite direction by increasing calcium levels in the blood.
- 22 amino acids: This may refer to other smaller peptides but is not the correct number for calcitonin.
- 12 amino acids: This is too short for calcitonin and is typically not associated with important hormones in calcium metabolism.
