How does the accumulation of H⁺ ions affect muscle function during intense exercise?

Correct option is C

The correct answer is (c).
Introduction
Intense exercise causes H⁺ accumulation (from lactic acid dissociation), lowering muscle pH. This acidosis inhibits key enzymes and disrupts cellular processes, contributing to fatigue.
Information Booster

• H⁺ ions accumulate from anaerobic glycolysis and ATP hydrolysis.
• Decreased pH impairs calcium binding and cross‑bridge cycling.
• Inhibits phosphofructokinase, slowing glycolysis.
• Leads to muscle fatigue and reduced force production.

• Option A: enzyme activity is inhibited.
• Option B: oxygen delivery not increased.
• Option D: glycogen synthesis not accelerated.