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_______ fluid represents 2/3 of Total Body Weight.
Question

_______ fluid represents 2/3 of Total Body Weight.

A.

Transcellular fluid compartment

B.

Interstitial fluid

C.

Intracellular fluid

D.

Extracellular fluid

Correct option is C


Ans: (c) Intracellular fluid
Sol. Intracellular fluid (ICF) accounts for approximately two-thirds (2/3) of the body's total fluid volume, making it the most abundant type of fluid in the human body. The majority of this fluid is contained inside the cells of the body.
The total body water is divided into two main compartments:
1. Intracellular Fluid (ICF): This is the fluid found within the cells. It constitutes about 60% of the body’s total water content and plays a vital role in maintaining cellular function. It is rich in potassium (K+), phosphate (PO₄³⁻), and magnesium (Mg²⁺).
2. Extracellular Fluid (ECF): This includes fluid outside the cells, which is about one-third (1/3) of the body’s total water content. It consists of:
· Interstitial fluid: Fluid found between the cells.
· Plasma: The liquid component of blood.
· Transcellular fluid: Specialized fluids like cerebrospinal fluid, synovial fluid, etc.
Intracellular fluid is crucial for maintaining cellular integrity and function. It helps regulate cell volume, maintains the cell’s osmotic balance, and provides a medium for the biochemical processes that occur within the cell, such as metabolism and protein synthesis.
Why Intracellular Fluid is Most Abundant:
· Cellular structure: Every cell in the body is surrounded by a membrane, and the majority of the fluid in the body resides inside the cells. These cells, such as muscle cells, red blood cells, neurons, etc., hold large amounts of water in the form of intracellular fluid.

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